Challenging the artificial distinction between social cognition and language, we launched the CLAPP project, which aims to better characterize language profiles in neurodegenerative diseases with predominant cognitive expression, such as the behavioral variant of frontotemporal dementia (bvFTD), Alzheimer’s disease (AD), and primary progressive aphasias (PPA), including the semantic, non-fluent, logopenic, and anarthric variants.

In collaboration with the memory resource and research centers (CMRRs) of Lille and Toulouse, we are retrospectively analyzing the language performance of over 160 patients using a standardized language assessment battery. This represents the largest French-speaking cohort of PPA patients, and one of the largest worldwide.